产品货号:
Z32097
中文名称:
CRK II抗体
英文名称:
Anti-CRK II Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CRK II Antibody |
指标别名 | Adapter molecule crk;CRK;CRKII;p38;Proto oncogene c Crk |
克隆性 | Monoclonal |
检验物种 | human,mouse,canine,rabbit |
应用范围 | WB |
基因名称 | CRK |
抗体来源 | Mouse |
免疫原 | Purified recombinant human Crk II protein fragments expressed in E.coli. |
计算分子量 | 34KD |
成分 | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH7.4,150mM NaCl) with 0.2% sodium azide,50% glycerol. |
纯化方式 | Affinity purification |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | CRK,also known as p38 or CRKII,is a protein that in humans is encoded by the CRK gene.This gene is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins.It is mapped to 17p13.3.The CRK protein participates in the Reelin signaling cascade downstream of DAB1.The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways,recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction.The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation.Two alternative transcripts encoding different isoforms with distinct biological activity have been described. |
Uniprot ID | P46108 |
基因名全称 | Adapter molecule crk |
蛋白名全称 | Adapter molecule crk |
推荐稀释比 | WB 1:1000~1:2000 |
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